Dr Tan Poh Seng

Senior Consultant, Gastroenterology & Hepatology

MBBS(Hons), MRCP (UK), M.Med(Int Med), FAMS, FRCP(Edin)

Scientific Publications

  • Seng Gee Lim Wah Wah Phyo Joanna Zhi Jie Ling Gavin Cloherty Emily K. Butler Mary C. Kuhns Anne L. McNamara Vera Holzmayer Jeffrey Gersch Wei Lyn Yang Jing Hieng Ngu Jason Chang Jessica Tan Taufique Ahmed Yock Young Dan Yin Mei Lee Guan Huei Lee Poh Seng Tan Daniel Q. Huang Htet Toe Wai Khine Chris Lee Amy Tay Edwin Chan. Comparative biomarkers for HBsAg loss with antiviral therapy shows dominant influence of quantitative HBsAg (qHBsAg). AP&T Nov 2020

  • Kew GS, Chen ZJ, A Yip WJ, Huang YWC, Tan LY, D Huang QY, Dan YY, Lee GH, Lee YM, Low HC, Lim SG, Gowans M, Muthiah MD, Tai BC, Tan PS. Identifying Patients with Cirrhosis who Might Avoid Screening Endoscopy Based on Serum Albumin and Bilirubin and Platelet Counts. Clin Gastroenterol Hepatol. 2019 Nov 8. Epub ahead of print.

  • Low EXS, Tripon E, Lim K, Tan PS, Low HC, Dan YY, Lee YM, Muthiah M, Loo WM, Koh CJ, Phyo WW, Pang J, Lim SG, Lee GH. Risk factors for ribavirin treatment failure in Asian organ transplant recipients with chronic hepatitis E infection. World J Hepatol. 2019 Jun 27; 11(6):553-561

  • Tan PS. Muthiah MD, Koh T, Teoh YL, Chan A, Kow A, Zheng Q, Kwon CHD, Lee GH, Lesmana CRA, de Villa V, Fung J, Lim K. Asian Liver Transplant Network Clinical Guidelines on Immunosuppression in Liver Transplantation. Transplantation 2019 Mar; 103(3): 470-480

  • Tan PS, Lim SG. Editorial: Hepatocellular carcinoma risk in the era of direct-acting anti-virals-is the case closed? Aliment Pharmacol & Ther. 2018 Jan;47(2):308-309 

  • Law JH, Tan JKH, Wong KYM; Ng WQ; Tan PS; Bonney GK; Iyer SG; Krishnakumar M; Kow WCA. Does persistent anti-HBc positivity influence the prognosis of HBsAg-negative hepatocellular carcinoma? Comparative outcomes of anti-HBc positive versus anti-HBc negative non-B non-C HCC. HPB (Oxford) 2018 

  • Poh Seng Tan, Badar Muneer, Smruti R. Mohanty, et al. Hepatoma. BMJ Best Practice Update. (2016, 2017, 2018)

  • Selva Rajoo A, Lim SG, Phyo WW, Tun T, Dan YY, Lee YM, Low HC, Lim K, Tan PS, Lee GH. Acute-on-chronic liver failure in a multi-ethnic Asian city: A comparison of patients identified by Asia-Pacific Association for the Study of the Liver and European Association for the Study of the Liver definitions. World j Hepatol. 2017 Oct 8;9(28):1133-1140.

  • Taouli B, Hoshida Y, Kakite S, Chen X, Tan P, Sun X, Kihira S, Kojima K, Toffanin S, Fiel MI, Hirschfield H, Wagner M, Llovet JM. Imaging-based surrogate markers of transcriptome subclasses and signatures in hepatocellular carcinoma: preliminary results. Eur Radiol. 2017

  • Hartono JL, Koh T, Lee GH, Tan PS, Muthiah M, Aw MM, Madhavan K, Kow A, Lim KB. Predictors of Non-adherence to Immunosuppressive Therapy in Asian Liver Transplant Recipients. Transplant Proc 2017 Jul-Aug;49(6):1419-1424.

  • Tan PS, Nakagawa S, Goossens N, Venkatesh A, Huang T, Ward SC, Sun X, Song W, Koh A, Canasto-Chibuque C, Deshmukh M, Nair V, Mahajan M, Zhang B, Fiel MI, Kobayashi M, Kumada H, Hoshida Y. Clinicopathological indices to predict hepatocellular carcinoma molecular classification. Liver Int. 2015 (IF 4.85)

  • Miltiadous O, Sia D, Hoshida Y, Fiel MI, Harrington AN, Thung SN, Tan PS, Dong H, Revill K, Chang CY, Roayaie S, Byrne TJ, Mazzaferro V, Rakela J, Florman S, Schwartz M, Llovet JM. Progenitor cell markers predict outcome of patients with Hepatocellular Carcinoma beyond Milan criteria undergoing liver transplantation. J Hepatol. 2015 Jul 25. pii: S0168-8278(15)00516-4. doi: 10.1016/j.jhep.2015.07.025. (IF 11.336)

  • Schmidt B, Wei L, DePeralta DK, Hoshida Y, Tan P, Sun X, Sventek JP, Lanuti M, Tanabe KK, Fuchs BC. Molecular subclasses of hepatocellular carcinoma predict sensitivity to fibroblast growth factor receptor inhibition. Int J Cancer. 2015 Oct 20. doi: 10.1002/ijc.29893 (IF 5.085)

  • Kishikawa T, Otsuka M, Tan P, Ohno M, Sun X, Yoshikawa T, Shibata C, Takata A, Kojima K, Takehana K, Ohishi M, Ota S, Noyama T, Kondo Y, Sato M, Soga T, Hoshida Y, Koike K. Decreased miR122 in HCC leads to chemoresistance with increased arginine. Oncotarget 2015;6(10):8339-8352. (IF 6.63)

  • Jacob V, Chernyavskaya Y, Chen X, Tan P, Kent B, Hoshida Y, Sadler KC. DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos. Development. 2015;142(3):510-21. (IF 6.27)

  • King LY, Canasto-Chibuque C, Johnson K, Yip S, Chen X, Kojima K, Deshmukh M, Venkatesh A, Tan P, Sun X, Villanueva A, Sangiovanni A, Nair V, Mahajan M, Kobayashi M, Kumada H, Iavarone M, Colombo M, Fiel MI, Friedman SL, Llovet JM, Chung RT, Hoshida Y. A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration. Gut 2014; (IF 13.32)

  • C Turato, A Vitale, S Fasolato, M Ruvoletto, L Terrin, S Quarta, R Ramirez Morales, A Biasiolo, G Zanus, N Zali, PS Tan, Y Hoshida, A Gatta, U Cillo, P Pontisso. SERPINB3 is associated with TGF-β1 and cytoplasmic β-catenin expression in hepatocellular carcinomas with poor prognosis. British Journal of Cancer (2014) 110, 2708–2715 (IF 4.82)

  • Poh Seng Tan, Myat Oo Aung, Seng Gee Lim, et al. Liver disease progression and virological response: entecavir rescue still possible in the setting of rtM204I lamivudine resistant mutation. Gut 2012;62(5):801-802. (IF 13.32)

  • Kensuke Kojima, Craig April, Claudia Canasto-Chibuque, Xintong Chen, Manjeet Deshmukh, Anu Venkatesh, Poh Seng Tan, Masahiro Kobayashi, Hiromitsu Kumada, Jian-Bing Fan, Yujin Hoshida. Transcriptome Profiling of Archived Sectioned Formalin-Fixed Paraffin-Embedded (AS-FFPE) Tissue for Disease Classification. PLoS ONE 9(1): e86961. doi:10.1371/journal.pone.0086961 (IF 3.234)

  • SG Lee GH, Lim K, Tan PS. RESISTANCE IS NO LONGER A PROBLEM WITH ENTECAVIR AND TENOFOVIR. Current Hepatitis Reports 2013. 

  • Hartono JL, Aung MO, Dan YY, Gowans M, Lim K, Lee YM, Lee GH, Low HC, Tan PS, Thwin MA, Soon C, Chiu LL, Khoo MJ, Koay E, Lim SG. Resolution of adefovir-related nephrotoxicity by adefovir dose-reduction in patients with chronic hepatitis B. Aliment Pharmacol Ther. 2013 Feb 21. doi: 10.1111/apt.12251. 

  • Lee GH, Aung MO, Dan YY, Lee YM, Mak B, Low HC, Lim K, Thwin MA, Tan PS, Lim SG. Do different lamivudine-resistant hepatitis B genotypes carry the same risk of entecavir resistance? J Med Virol. 2013 Jan;85(1):26-33. 

  • Ng SC, Tang W, Ching JY, Wong M, Chow CM, Hui AJ, Wong TC, Leung VK, Tsang SW, Yu HH, Li MF, Ng KK, Kamm MA, Studd C, Bell S, Leong R, de Silva HJ, Kasturiratne A, Mufeena MN, Ling KL, Ooi CJ, Tan PS, Ong D, Goh KL, Hilmi I, Pisespongsa P, Manatsathit S, Rerknimitr R, Aniwan S, Wang YF, Ouyang Q, Zeng Z, Zhu Z, Chen MH, Hu PJ, Wu K, Wang X, Simadibrata M, Abdullah M, Wu JC, Sung JJ, Chan FK; Asia–Pacific Crohn's and Colitis Epidemiologic Study (ACCESS) Study Group. Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study. Gastroenterology. 2013 Jul;145(1):158-165.e2.

  • Ang D, Teo EK, Tan A, Ibrahim S, Tan PS, Ang TL, Fock KM. A comparison of surgery versus transcatheter angiographic embolization in the treatment of nonvariceal upper gastrointestinal bleeding uncontrolled by endoscopy. Eur J Gastroenterol Hepatol. 2012 Aug;24(8):929-38.

  • PS Tan, EK Teo, KM Fock, et al. Massive obscure-overt upper gastrointestinal bleeding secondary to hemobilia. Endoscopy. 2009; 41 Suppl 2:E294-5.

©2019 by PS Tan Digestive & Liver Centre.